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Network pharmacology enhances the precision of drug discovery by linking pharmacological targets to disease mechanisms through target prediction algorithms and functional enrichment analyses, such as Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway mapping (Singh et al., 2022)

5.1 Immune-inflammatory pathways As the largest immune organ in the human body, the gut harbors 70% of immune cells and coordinates immune function through microbial metabolites such as SCAFs, thereby regulating neuroinflammatory responses (Mann et al., 2024)

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