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This shift is what leads to reduced pain and restored function

As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period

The disease usually starts with insulin resistance, which occurs when cells do not use insulin properly

(2012) demonstrated that It could improve cognitive function in models of Alzheimers disease by promoting neuronal repair and synapse formation, suggesting its potential as a therapeutic for neurodegenerative conditions