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The ROS scavenging property of Sp was also replicated in the Drosophila models knocked-down for essential antioxidant enzymes catalase and glutathione peroxidase, where neuronal cells of 15 days AEL flies genetically expressing a redox biosensor, roGFP showed reduced fluorescence under Sp treatment (Fig

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To view or add a comment, sign in Ahead of print MALAT1 modulates granulosa cells ferroptosis and apoptosis through PAK2 upregulation in polycystic ovary syndrome Highlights MALAT1 controls ferroptosis in KGN granulosa cells, uncovering a novel lncRNA-driven cell-death pathway in ovarian physiology