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For biological safety, some MOFs (e.g., ZIF-8, UiO-66) exhibit controllable degradation behavior under physiological conditions, demonstrating a good short-term biocompatibility

Concerning the molecular mechanisms implicated in HGF angiogenic role, there is a strong association with the E-twenty-six (Ets) pathway, which is implicated in the regulation of developmental and mitogen signals (Aoki et al., 2000)

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Therefore, the localization of melanocytes places them in constant contact with pro-oxidative factors, and excessive exposure to these factors means that melanocytes might be more exposed to oxidative stress than other cells 17