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It is perhaps the key question about BPC-157

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There is an excellent presentation from Cambridge University which outlines this: [First trimester embryonic nutrition

Infection of tobacco with different types of bacteria revealed that incompatible pathogens, their hrp mutants, and non-pathogenic bacteria induce high levels of defense gene expression, including that of the above mentioned GST ( EBR-52) , while virulent pathogens induce only a limited response