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doi: 10.1016/j.freeradbiomed.2021.10.035

Most oncologists advise against GH-enhancing compounds for anyone with active cancer or high cancer risk

DSIP typically requires continuous nightly use for optimal benefits, though some patients successfully implement 5-days-on, 2-days-off schedules to prevent potential tolerance development

In a sensitivity analysis restricted to placebo-controlled ALC monotherapy trials (4 studies), the pooled estimate also favored ALC (SMD 2.41, 95% CI 4.43 to 0.39