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Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on January 26th, 2026

It is the most common of all enzymopathies (diseases caused by abnormalities of enzymes), and some 140 genetic variants of the enzyme have been distinguished

Furthermore, this study also confirmed that liproxstatin-2, a new ferroptosis inhibitor, possessed a prophylactic and therapeutic benefit in alleviating LN patient serum-induced renal tubular epithelial cell ferroptosis[158]

This often-misdiagnosed condition affects the small, unmyelinated nerve fibers responsible for pain, temperature sensation, and autonomic functions, leading to symptoms that can range from mild discomfort to debilitating pain and dysfunction