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Methods Animals and ethics statement Previous studies have shown that diabetes attenuates the protective ability of females, who are more in favor of sweet foods, against the development of cardiac diseases and nephropathy 10

These combinations are not limited to enzymatic PTMs, and PDB could also be coupled to approaches such as T-REX (targetable reactive electrophiles and oxidants) that specifically modifies redox-sensitive proteins via electrophiles (Parvez et al., 2016

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In addition, deletion of the miR-483-3p-responsive elements in binding site 2 of the IGF-1 3 UTR resulted in abrogation of the inhibitory effect of miR-483-3p, indicating that only site 2 was functional (Fig