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Where comparisons were made between the trial cohort and the matched control cohorts, these were univariatei.e

-Synuclein aggregates evoke microglia activation which in turn promotes aggregated protein propagation to other brain regions, possibly even from the gut or periphery to the brain 27,33

59 Furthermore, chronic inflammasome activation has been linked to metabolic disorders such as obesity and type 2 diabetes, contributing to systemic inflammation and hepatic dysfunction

While natural dietary intake is ideal for overall health, supplements may be considered in specific cases, but only after consultation with a qualified dermatologist or plastic surgeon who can advise on the appropriate form, dosage, and duration