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The binding of WAVE protein to the SH3 domain of IRSp53 leads to the release of intramolecular inhibition of IRSp53 (Miki et al., 2000

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TMAO enhances TNF- mediated fibrosis and release of inflammatory mediators from renal fibroblasts

Oral delivery of MnLR with glycerol effectively prevents orthotopic primary colon tumor occurrence and liver metastasis in mice Inspired by the aforementioned capability of MnLR/Gly to initiate systemic antitumor immunity, we subsequently investigated its potential effectiveness in preventing the occurrence of primary colon cancer and mitigating distant metastasis, which is crucial for substantially reducing cancer mortality rates