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Our approach contains some further limitations: Drug interactions cannot be taken into account as we just do not have any toxicological data on such effects (e.g

This means while smoking does not directly cause eating disorders, it can contribute to their development

The New Zealand experience tells a very different story

The nicotine concentrations in SLT products ranged from 4.67 to 28.23 mg/g (Table 1), average was 12.84 and the coefficient of variation was 83.96%, The unprotonated nicotine was calculated by putting the product pH and appropriate Pka into the Henderson-Haselbalch equation 29 it ranged from 0.10 to 99.1% and the coefficient of variation was 71.38%, indicating great heterogeneity across brands