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Because its benzyl alcohol preservative suppresses bacterial growth, which supports drawing from a reconstituted solution repeatedly over a multi-day window

In 2003, a Cochrane review of three RCTs on cognitive function in patients with AD or other forms of cognitive impairment also found no evidence of benefits of B12 on cognitive function compared with placebo

0.25 to 0.5 mg Once or twice daily 4 to 8 weeks Subcutaneous, 1 to 2 inches from lateral epicondyle Moderate to severe lateral epicondylitis, chronic cases Starting with a conservative dose makes sense for most people

People who may be at a higher risk for B12 deficiency include older adults, those with gastrointestinal disorders, vegetarians and vegans, and those who have had gastrointestinal surgery