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When used in combination with clomiphene citrate or letrozole, NAC increases ovulation and pregnancy rate in infertile females suffering from PCOS and positively affects the quality of oocytes and number of follicles 18mm

The increase in CYS or CYSS here could be attributed to the action of the enzyme of -GT in degrading GSH ( In this study, it was interesting to notice that the ratio of CYS/CYSS in SI1 digesta was the highest in the HGSH group at d5 and 14, while on the other hand, the CYS/CYSS ratio was the lowest in SI2 digesta at d5

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