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[DOI] [PubMed] [Google Scholar] 170.Sandborn WJ, Feagan BG, Marano C, Zhang H, Strauss R, Johanns J, et al

Glutamine starvation by glutaminase inhibitior, transporter inhibitor, or glutamine depletion has shown to have significant anti-cancer effect in pre-clinical studies

2019), and it also provides evidence for the deficiency of protease activity in the loss-of-function mutant form of hHPN RS

Similar observations were noted in later human studies [56, 57], with the peak serum TMAO observed within hours following oral administration of the tracer [56]