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Patients with severe gastrointestinal conditions, such as gastroparesis or other disorders that affect gastric motility, may also experience worsening symptoms since semaglutide slows gastric emptying

This connection to an endogenous protective factor, combined with the breadth of preclinical research showing activity across multiple physiological systems, has contributed to the peptide's popular attention

Glutathione plays a crucial role in protecting cells from oxidative stress and free radicals

Despite the fact that peptide ligands are relatively flexible and have a lower binding affinity to receptors compared with antibodies, the use of peptides in theranostic nanomedicine offers advantages because they are smaller, have reduced immunogenicity, have high multivalency, penetrate deep into tumors, are simpler to synthesize, and are cost-effective in production