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On a therapeutic note, some microbiota-targeted treatments have reduced protein aggregates in models: long-term broad-spectrum antibiotics reduced A deposition and microglial reactivity in an AD mouse model, and recolonization with a simplified microbiota reversed some of these effects, indicating that specific microbial communities can either exacerbate or ameliorate protopathic cascades [102]

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This protection slows the cascade of damage that leads to dullness, rough texture, and visible signs of photoaging such as uneven tone and surface roughness

At present, treatment with levodopa is the most effective way to relieve tremor, stiffness, and slow movement associated with PD