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Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic Alzheimers disease mouse model

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Further, BBB disrupts transiently by breaking down the TJs so that it can permit transport of various molecules, ultrasounds (trans-skull focused ultrasound (FUS), MRI, or hyperosmotic solutions (like mannitol, arabinose, lactamide, saline, urea, DMSO, ethanol, glycerol, polysorbate-80, and X ray-irradiation, etc.)