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5.1 Focus on Smokers with CV Disease Several meta-analyses showed that both varenicline and combination NRT are more effective than bupropion or single NRT in smokers suffering from a chronic CV disease [4], making the first two approaches the first-line therapies for smoking cessation in patients with a history of CV disease (see Table 3)

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Abstract Maternal tobacco use and nicotine exposure during pregnancy have been associated with adverse birth outcomes in infants and can lead to preventable pregnancy complications