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Oxidative stress and mitochondrial dysfunction Dox triggers cardiotoxicity via pronounced oxidative stress and mitochondrial dysfunction, driven by redox cycling and excessive generation of reactive oxygen species (ROS) which might disrupt the balance between oxidants and antioxidant defenses

32 , e4221 (2024)

Second, safety profiles of approved peptides are generally favorable, with most adverse effects being mild to moderate and manageable through appropriate clinical monitoring and patient education

The management of patients include patient-reported outcomes for long-term follow-up care and for early detection of possible adverse events and the use of digital technologies, such as telemedicine - videoconferences for patients follow-up and reinfection risk elimination, digital therapeutics approach, especially for non-pharmaceutical interventions (e.g., breathing exercises), electronic control of body parameters such as temperature, oxygen saturation, blood pressure, that can be measured with wearable devices and the data can be analyzed with artificial intelligence (256, 257)