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A randomized placebo-controlled trial that included 1,312 individuals with type 2 diabetes demonstrated that 1 gram of EPA and DHA, plus 50 mcg (2,000 IU) of vitamin D, taken daily for five years had no effect on the progressive loss of kidney function

140 Thus, cysteine contributes to the inhibition of ferroptosis both as a component of glutathione, which facilitates the scavenging of lipid peroxides by the phospholipid hydroperoxidase glutathione peroxidase 4 (GPX4), and as a substrate of NFS1

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