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But you would not guess from its gloss that vaping is something like 95 percent safer than smoking, that potentially harmful substances in e-cigarette aerosol are typically present only in trace amounts, or that smokers who switch to vaping see big reductions in blood levels of toxins and carcinogensat least as big as the reductions seen in smokers who switch to FDA-approved "nicotice replacement therapy" such as gum and patches

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(Combustion is what causes the creation of noxious gasses such as carbon monoxide)

Many characteristics of these trials, such as short durations, confined settings and choice of comparators and participants, are not representative of real-world use and fail to adequately investigate whether HTPs reduce harm and are beneficial to public health