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Future clinical research should investigate the effects of opioid antagonism on the individual ketamine enantiomers and include measurements of relevant metabolites to confirm that observed effects are due primarily to pharmacodynamic interactions rather than alterations in the metabolism or clearance of ketamine
In experiments by Vittone et al., 12-hour mean growth hormone concentrations apparently rose from about 1.1 0.9 g/L to roughly 2.2 1.9 g/L, while the integrated 12-hour growth hormone output increased from around 1,114 931 to about 2,032 1,728 gmin/L
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Modern Pathology 36(1), 2023
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