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Efficacy and safety of coenzyme Q10 in heart failure: a meta-analysis of randomized controlled trials

The most cited concern is the same as for GH therapy: IGF-1 elevation has a complex relationship with cancer risk in epidemiological studies, with some analyses suggesting higher IGF-1 correlates with increased risk of certain cancers, while others find the opposite in older populations where IGF-1 is already low [16]

Foods That Tax the Liver As noted, glutathione is processed in the liver so having foods that consistently strain the liver are likely to decrease glutathione levels