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R389Q mouse model, suggesting that inflammation could be a major component of the pathology in the neurodegeneration of FDXR mutations [86] NDUFV1 deficiency (OMIM # 618225) NADH: ubiquinone oxireductase flavoprotein 1 (NDUFV1) is a 51-kDa highly conserved nuclear encoded subunit comprising the electron input (N) functional module of Complex I [87] )

CrossSectional Epidemiological Profile According to the Global Burden of Disease, Injuries, and Risk Factors Study (GBD), PD affected an estimated 11.67 million individuals globally and was associated with approximately 0.42 million deaths in 2023

1,000 mg/day) compared to placebo (99)