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In addition, vitamin B12 is necessary for myelin sheath and nerve conduction, for neurotransmitters and brain metabolism, and for maintaining mood

Supports endothelial cell proliferation and migration : VEGFR2 modulation is associated with increased fibroblast activity and early connective tissue regeneration in transected ligament models 4

This puts vegans and vegetarians at a higher risk of deficiency, as plant-based diets lack adequate amounts of this essential nutrient

It is essential that clinical trials can be developed to effectively compare these routes of administration and that clinicians can share their experiences with these modalities of B12 administration so that they can be popularised and considered as viable alternatives for patients