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For those seeking maximum anti-aging efficacy and willing to work within its formulation constraints, GHK-Cu is the stronger choice

These continuously generated electrophilic hydroperoxy-phospholipids are neutralized by a specific GSH-dependent peroxidase, glutathione peroxidase 4 (GPX4), which prevents them from damaging membranes and driving ferroptotic cell death (7, 8)

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Notably, the plasma formaldehyde levels in our Aldh2*2 KI mice after AA exposure are comparable to those reported in Aldh2 / Adh5 / mice, which exhibit perinatal lethality and lymphopenia [89], suggesting that excessive accumulation of formaldehyde alone can cause severe systemic toxicity including immunotoxicity