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8-Hydroxy-2-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures

The oxidized forms are subsequently reduced back to their original state by reductive enzymes, allowing recycling within the antioxidant system

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A systematic review analyzing zinc supplementation in PCOS found that doses ranging from 4 to 50 mg daily for 8 to 12 weeks resulted in improvements in insulin resistance (HOMA-IR) and lipid profiles while also reducing inflammatory markers such as hs-CRP and oxidative stress markers like malondialdehyde (MDA) and TAC [153]