(History + Background) IGF-1 DES , or Insulin-like Growth Factor 1 DES(1-3) , is a modified version of IGF-1 a powerful anabolic growth factor that plays a critical role in: Muscle growth Tissue repair Recovery Cellular regeneration It is essentially a truncated form of native IGF-1: 13 amino acids shorter than full-length IGF-1 Lacks the first three N-terminal amino acids (hence the name DES(1-3) ) This structural modification gives IGF-1 DES two unique properties: Greatly increased receptor binding affinity 10x more potent locally vs
Borthakur G , Popplewell L, Boyiadzis M, Foran J, Platzbecker U, Vey N, Roland W, Olin R, Raza A, Giagounidis A, Ottmann O, Al-Kali A, Jabbour E, Kadia T, Garcia-Manero G, Bauman J, Wu Y, Liu Y, Schramek D, Zhu J, Wissel P, Kantarjian H
A., Elsaid, K., Olabi, A
Effect of radial nerve release on lateral epicondylitis outcomes: a prospective, randomized, double-blinded trial