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Acts partially through local GI mucosal pathways and partially via systemic absorption

EC 1.15.1.1) 2 O 2 + 2 H + H 2 O 2 + O 2 peroxynitrite (ONOO ), via the reaction with nitric oxide (NO) O 2 + NO ONOO hydroperoxide radical (HOO) O 2 + H + HOO Catalytic mechanism of G6PD The catalytic mechanism of glucose 6-phosphate dehydrogenase has been studied in great detail in the microorganism Leuconostoc mesenteroides , whose enzyme displays the unusual ability to use NAD + and/or NADP + as coenzyme

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Bradford assays Bradford assay was either purchased from Pierce or made in-house as described by Bradford 1972 [27]