Marco Vacante, University of Catania, Italy Updates Copyright 2021 Wang, Wang, Yang, He and Wang
Targeting ER stress-e.g., via chemical chaperones or antioxidantsmay inhibit ferroptosis, representing a potential therapeutic strategy for COPD (69)

Symptoms can include: Temporary amnesia of the injurious event Decreased concentration or brain fog Difficulty learning new material Headache or blurred vision Sensitivity to noise or light Emotional lability (involuntary laughing or crying) Anxiety or depressed mood Fatigue Sleep dysfunction Dizziness or imbalance Nausea or vomiting Physical weakness Slurred speech 5 DANGER SIGNS Seek immediate medical attention for anyone exhibiting any of the following symptoms: A change in consciousness, manifesting as difficulty staying awake or alert, not making sense when talking, or not being able to understand what is being said Progressively worsening headache An increase in nausea or vomiting Pronounced physical weakness Slurred speech If none of the five big danger signs above are present, then it is ok to treat symptoms at home, following some basic guidelines: Plan a slow return to activity

For example, carvacrol upregulates GPX4 expression to slow the progression of lipid peroxidation, thereby inhibiting ferroptosis and showing potential for treating cerebral ischemia [124]