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Subsequently, twenty prediabetic KKay mice were enrolled and randomly divided into two groups using a computer-generated randomization schedule (n = 10 per group)

3) and several interacting residues are conserved across enteroviruses (Fig

This finding triggered the amyloid hypothesis, which is the idea that APP cleavage products, such as A42, are the fundamental cause of AD, eventually leading to synaptic dysfunction, gliosis, neuronal loss, and tau pathology (Hardy, 2009)