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The Beighton score is a popular screening technique for generalized hypermobility

Intervention with different concentrations of sodium fluoride in osteoblasts led to an increase in intracellular ROS levels, a decrease in proliferation, and cell cycle arrest at the S phase (DNA synthesis phase), suggesting that sodium fluoride may suppress proliferation and block cell growth by increasing oxidative stress (38)

(2021) 6:e10209