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Nuttall et al.[37] studied the effect of chronic ingestion of therapeutic doses of APAP (1 gram, 4 times per day, for 2 weeks) on serum antioxidant capacity, and found a gradual and progressive decline to a level about 85% of control value

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3 Results 3.1 FOXO4-DRI effectively improves vascular function in naturally aging mice FOXO4-DRI has made great progress in anti-aging research, but there has been little research on it in the cardiovascular field, especially in the study of vascular aging

More studies should be conducted to fortify the blood-brain barrier and decrease cytokine-induced inflammation by targeting the oxidative cascade and preventing oxidative stress by enhancing mitochondrial function