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Science 276:16991702, PMID: 9180080 Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K (2012) l-glutamate released from activated microglia downregulates astrocytic l-glutamate transporter expression in neuroinflammation: the collusion hypothesis for increased extracellular l-glutamate concentration in neuroinflammation

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Calcium ions also have a dual effect on adenylate cyclase