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Its the question that all of my films ask. And as if to emphasize whats at stake, Scorsese quite appropriately begins his film with Neil Youngs rollickingly nihilistic mid-seventies smack anthem Time Fades Away. With its oscillation between a verse about hustling and heroin, and a paternalistic chorus that cautions, Son, dont be home too late, the song aptly prefigures the portrait of generational dissolution to come

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Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice

These effects worsen when combined with alcohol or other sedatives