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In summary, the information in this paper covers the journey from the basic physiological mechanisms for glutathione synthesis and regulation through to how glutathione ameliorates free radical imbalances at the organ system level (Figure 2)

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[1] [6] Severe deficiencies may include symptoms of reduced heart function, suppression of bone marrow, as well as more various severe neurological symptoms possibly including sensory loss, abnormal balance and reflexes, memory and consciousness impairment, smell and taste problems, depression, irritability, confusion, and psychosis

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