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Furthermore, CoQ10 increases glucocorticoid receptor expression while reducing immunophilins (FK506-binding protein 5, FKBP5) and hydroxysteroid dehydrogenases (HSD11B1), thereby promoting oocyte maturation (Ruiz-Conca et al., 2022)

NHS (diluted 1:200 in veronal buffer) (Complement Technologies), pure human C1q (diluted to 0.366 g/mL in veronal buffer) (Complement Technologies) or pure mouse C1q (diluted to 0.366 g/mL in veronal buffer) (Prospecbio) was added and the plates incubated at 37 C for 30 min

But in addition to that, some environmental stress factor probably triggers it

Solution: Use a gentle moisturizing scalp treatment between peptide applications