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Cyanocobalamin Synthetic Vitamin B12 As we have discussed, for many years B12 supplements mainly contained cyanocobalamin , a synthetic form of B12 that is not directly bioactive and is only found naturally in the body or diet in minor traces

However, there is considerable individual variation, and many patients notice little change initially

The blend is particularly attractive for research applications where comprehensive tissue repair is being studied, as it addresses multiple aspects of the healing cascade simultaneously - from initial inflammation modulation through vascularization to final tissue remodeling