Browse Protocols by Category Weight Management & Metabolic Peptides These protocols cover GLP-1 receptor agonists and related compounds studied for weight loss, appetite regulation, and metabolic health
Grangeon M, Tomasini P, and Chaleat S, et al (2019) Association between immune-related adverse events and efficacy of immune checkpoint inhibitors in non-small-cell lung cancer Clin Lung Cancer 20 (3) 201207 81

Potential benefits Promotes libido 1, 5, 7 Aids in sexual receptivity 1, 5 Relaxes smooth muscle and promotes blood flow 6 Helps with rapid onset of arousal 1, 4, 5 Promotes erection quality and sensitivity 1 May address premature ejaculation 1, 3 Flexible dosing options for varied lifestyles The medication is designed to work when there is an initial sexual stimulus Dose adjustments should aim for the lowest appropriate dose to potentially limit adverse effects, support adherence and based on response as determined by the prescriber Adverse Effects Nausea 8-11 Flushing 8-10 Headache 8,9,11 Changes in heart rate 8,9,11 Changes in blood pressure 8,9,11 Dizziness 8,9,11 Vision changes 8,9 Muscle or back pain 8,9 Uterine contraction (in postpartum women) 11 Serious Adverse Effects Hyperpigmentation 11 Priapism (erection lasting longer than 4 hours) 8,9 Contraindications Not suitable for individuals with history of cardiovascular disease 8,9,11 Drug Interactions Use of nitrates such as Nitroglycerin 8,9 Use of guanylate cyclase (GC) stimulators such as Riociguat 8,9 Handling requirements Keep away from children and pets Olympus Peak Max combines oxytocin, bremelanotide, and tadalafil to support sexual wellness in men

The binding free energy value serves as an indicator of the binding strength between the ligand and protein, wherein a lower value corresponds to a more favorable docking orientation and a stronger binding interaction