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For example, the expression of ALOX15 is mediated by spermidine/spermine N1-acetyltransferase 1, a tumor protein p53 (TP53) target gene, and is involved in TP53-mediated ferroptosis (Ou et al., 2016)
Allicin can oxidize glutathione, lowering cellular concentration of GSH
doi: 10.3389/fmolb.2022.1016090 Received 18 August 2022 Accepted 15 September 2022 Published 29 September 2022 Volume 9 - 2022 Edited by Ye Sun, Boston Children's Hospital, Harvard Medical School, United States Reviewed by Xudong Wang, Massachusetts General Hospital, Harvard Medical School, United States Xiujuan Shi, Tongji University, China Updates Copyright 2022 Ma, Yang, Zuo and Huang