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In some embodiments, the otic formulation or composition contains at least one viscosity modulating agent that provides the otic formulation or composition with a viscosity of about 2 cP, about 5 cP, about 10 cP, about 20 cP, about 30 cP, about 40 cP, about 50 cP, about 60 cP, about 70 cP, about 80 cP, about 90 cP, about 100 cP, about 200 cP, about 300 cP, about 400 cP, about 500 cP, about 600 cP, about 700 cP, about 800 cP, about 900 cP, about 1,000 cP, about 5,000 cP, about 10,000 cP, about 20,000 cP, about 50,000 cP, about 100,000 cP, or about 250,000 cP
Upregulated GH receptor mRNA and protein in tendon fibroblasts Effect was dose-dependent and observed within 24 hours Provides a mechanistic link between BPC 157 and tissue growth/repair BPC 157 and blood vessels2019Vascular Review of BPC 157s vascular effects: promotes angiogenesis, protects endothelium, and counteracts vascular disruption in multiple injury models including thrombosis and ischemia-reperfusion
Dec 2020;41(6):1084-1091
