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Tirzepatide is a synthetic dual hormone agonist designed to activate both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor activity

The therapy involved an intragastric bolus, and continuous oral application in drinking water, activated azygos vein direct blood delivery, counteracted/attenuated the intracranial (superior sagittal sinus), portal and caval hypertension, aortal hypotension, multiorgan failure (brain, heart, lung, liver, kidney, stomach, and intestinal lesions), and progressing thrombosis

Use D50.0 for chronic blood loss anemia

The GPCR heterotetramer: challenging classical pharmacology