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Abbreviations ADI-R: Autism diagnostic interview - revised ALAD: Delta aminolevulinic acid dehydratase CARS: Childhood Autism Rating Scale CNS: Central nervous system d.f.: Degrees freedom DSM: American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders fGSH: Free reduced glutathione GCL: Glutamate cysteine ligase GCT: -glutamyl cyclotransferase GGT: -glutamyl-transferase GPx: Glutathione peroxidase GSH: Reduced glutathione GSH: GSSG: Glutathione redox ratio GSH-R: Glutathione reductase GS: Glutathione synthetase GSSG: Oxidised glutathione GST: Glutathione-S-transferases Mg 2+ : Magnesium ions Mn 2+ : Manganese ions Q: Cochran's Q (a measure of statistical heterogeneity) SMD: Standardised mean difference tGSH: Total glutathione References Wing L, Gould J: Severe impairments of social interaction and associated abnormalities in children: epidemiology and classification

Int J Mol Sci 20:728 Acknowledgements The author (AM) would like to acknowledge the infrastructure and facility provided by the National Institute of Pharmaceutical Education and Research (NIPER), Guwahati and the Department of Pharmaceuticals, Ministry of Chemicals, and Fertilizers, Government of India

Specifically, it consists of amino acid residues 176 through 191 of the human growth hormone sequence, with a tyrosine substitution at the terminal end

These curves invert and cortisol begins to break us down in the same way while the hormones which maintain our uniquely male and female appearance diminish