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J Neurol Neurosurg Psychiatry

For analysis of genes expressed, TaqMan probes for human IFNG , IFITM3 , IFI27 , IFI44L , IFIT1 , MX1 , ISG15 , MX2 , RSAD2 and SIGLEC1 , mouse Ndusf8 , Sdha , Sdhb , Sdhc , Txnrd1 , Got1 , Arg1 , Tgfb1 , Ccl2 , Ccl3 , Fn1 , Mmp2 and Mmp12 or viral N1 and N2 (SARS-CoV-2) (IDT) were used

This does not affect reconstitution, but it means the mechanism of action differs

Both of these approaches increase the permeability of the bacterial membrane, stimulate drug uptake, increase the achievable intracellular concentration of antibiotic drugs and thereby increase bactericidal efficacy (See Fig