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Trials such as CAMERA and GIPS-III suggest slowed atherosclerosis progression or improved postmyocardial infarction remodeling, whereas others show no clear cardiovascular benefit

After 4-day culture, organoids were dissociated in organoid dissociation solution (bioGenous, E238001) for 2 min at 37 C according to the manufacturers protocol, centrifuged at 68 g for 2 min, resuspended in organoid culture medium, and cultured as described above for organoids passaging

Together with other changes that we have found, this might be a reason for the improved resistance of the old rat heart to I/R that we observed

While these medications effectively decrease acid levels, they fail to address the underlying mechanical dysfunction allowing reflux to occur