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Earlier observations of Pryor and his associates (8) suggested that the principal relatively stable radical in cigarette tar might be quinone/hydroquinone/semiquinone complex which was an active redox system and that this redox system was capable of reducing molecular oxygen to produce superoxide, leading to hydrogen peroxide and hydroxyl radicals, which may eventually lead to oxidative damage of biological macromolecules

One showed yellowed teeth and a cancerous lip

Biomarker studies suggest reduced exposure to some toxicants, but nicotine and carbon monoxide levels may not change significantly

"It's a highly effective measure, and that's why they've opposed it for so long, and that's why we place great emphasis on it."