Symptoms of B12 deficiency can appear in years because the body naturally stores the vitamin in the liver
As abrupt changes in the profile of adverse events are unlikely despite increasing contraindications with higher ages, our data suggest an age-bias in decisions regarding secondary prophylaxis in AIS/TIA patients in Germany
Gaps between vials allow the medication to clear your system partially, which can lead to temporary return of appetite and other symptoms
Specific situations requiring medical review include: Severe or persistent gastrointestinal side effects from Mounjaro that significantly limit your food intake for more than a few days You are taking metformin in addition to Mounjaro, as this combination increases B12 deficiency risk You have a history of pernicious anaemia, gastric surgery, or conditions affecting nutrient absorption You are considering stopping B12 injections whilst taking Mounjaro You experience any unexplained neurological symptoms Urgent medical attention is needed if you develop severe, persistent abdominal pain (which may radiate to the back), persistent vomiting, fever, or yellowing of the skin/eyes, as these could indicate pancreatitis or gallbladder problems Your GP or practice nurse can arrange blood tests to check your B12 levels (serum B12, holotranscobalamin, and if borderline, methylmalonic acid levels may be used where available) and determine the appropriate frequency of B12 injections if deficiency is confirmed
