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By restricting excessive glycolytic flux and promoting the mitochondrial oxidation of pyruvate, cardiomyocytes achieve higher ATP production efficiency while avoiding lactate accumulation, intracellular acidification, and excessive generation of reactive oxygen species (64, 65)

10.1007/s10545-010-9253-9 J

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These receptors, including B-cell lymphoma 2/adenovirus E1B 19-kDa-interacting protein 3 (BNIP3), BNIP3-like (BNIP3L), FUN14 domain-containing protein 1 (FUNDC1) and the activating molecule in BECN1-regulated autophagy protein 1 (AMBRA1), would bind with LC3 to form autophagosome (Xiao et al., 2017