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Salidroside, a natural phenylpropanoid glycoside isolated from Rhodiola rosea , has been shown to enhance mitochondrial complex I activity by upregulating and phosphorylating AMPK2, increasing cardiomyocyte tolerance to I/R injury and reducing ferroptosis

The influence of sex hormones on musculoskeletal pain and osteoarthritis

Furthermore, ROS interacts with cellular transduction pathways like protein kinase C/extracellular signal-regulated kinases (ERK)/mitogen-activated protein kinase (MAPK) pathway that can affect cell growth, cell proliferation, differentiation, apoptosis and gene expression [10, 11]

European Journal of Paediatrics