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This process is inherently regulated by somatostatin, the body's "braking" hormone, which helps prevent the excessive, unnatural spikes often seen with direct hormone administration

Understanding this is the foundation for understanding why peptide-based approaches to GH optimisation have attracted serious clinical interest

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b , Immunoblot of indicated proteins in whole cell lysates and mitochondria isolated from HEK-293T (top) and HeLa (bottom) SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA